When it comes to shopping for a wrinkle cream, it all comes down to ingredients that promote collagen production and increase cellular turnover, Dr. Yadav says. “The number one ingredient I recommend to those looking to combat wrinkles is retinol,” she adds. Retinol can help firm and strengthen skin from the inside out, while smoothing the skin’s surface to fade the look of wrinkles,” she explains.

Other ingredients you can look for are alpha-hydroxy acids like glycolic, lactic, and mandelic acid. These increase cellular turnover, though they don’t aid in the production of new collagen. However, these ingredients do help resurface the skin for a smoother appearance, Dr. Yadav says.

In addition to these acids, Dr, Saedi also recommends seeking out vitamin C, peptides, niacinamide, and hyaluronic acid, which can also improve the appearance of fine lines and wrinkles.

If you’re looking for significant improvements in your skin’s texture and appearance, you may want to talk to your dermatologist about using tretinoin, Dr. Jhin adds. “While both are derived from Vitamin A, tretinoin is 20 times stronger than retinol, and is the only ingredient FDA-approved to treat signs of aging,” she explains. “Tretinoin works by increasing skin turnover, meaning your skin cells will divide and regenerate more rapidly to reveal newer, healthier and smoother skin beneath, while also reducing the appearance of skin discoloration.”

Tretinoin also targets wrinkles by boosting collagen production and elastin, which can lead to a more youthful appearance and smoother, tighter skin, Dr. Jhin adds. Just be weary that you’ll need a prescription for it.