Certain supplements have sometimes been thought to be helpful for menopause, but Dr. Rosser advises against them for a variety of reasons. For example, kava has been said to decrease anxiety and hot flashes—but the FDA has issued a warning about kava because of its potential to damage the liver, according to NAMS.

When it comes to supplements like evening primrose oil, phytoestrogens, dong quai, red clover, and black cohosh, NAMS notes that there’s not conclusive research to support their potential benefits when it comes to menopause. And with some of these supplements, the potential side effects could be problematic. For example, side effects of evening primrose oil can include inflammation, problems with blood clotting and the immune system, nausea, and diarrhea, according to NAMS.